Drug Discovery Biology
February 20, 2025
Thermodynamic Ballet: Enthalpic-Entropic Compensation in Biomolecular Handshakes
Enthalpy-entropy compensation epitomizes the complexity of biomolecular recognition.
Drug Discovery Biology
Drug Discovery Biology
February 20, 2025
Structural Secrets of SRβ GTPase: Unlocking the Ancient Code of Eukaryotic Membrane Traffic
SRβ, the oldest Ras-family member, connects billion-year-old innovations to modern eukaryotic secretory processes through its structural simplicity and regulatory sophistication.
Drug Discovery Biology
February 6, 2025
Oncotherapeutic Transmutation: The Role of Organoid Drug Testing in Precision Medicine for Peritoneal Carcinomatosis
Organoids empower clinicians and researchers to transcend standardized treatments, enabling the customization of therapies to the specific biological traits of each patient’s tumor.
Drug Discovery Biology
January 23, 2025
Breathing New Life into Research: The Promise of Advanced Lung Organoids in Respiratory Disease Modeling
In the quest to understand and treat pulmonary diseases, lung organoids stand at the forefront, offering a window into the complexities of the respiratory system.
Drug Discovery Biology
November 5, 2024
Unlocking Cellular Fate: The Science Behind Direct Reprogramming in Cellular Reprogramming
By leveraging the extraordinary potential of elite cells, scientists could revolutionize cellular reprogramming, paving the way for groundbreaking treatments for degenerative diseases, injuries, and even the aging process.
Drug Discovery Biology
October 14, 2024
Powering Cellular Highways: From Kinesin Discovery to Pharmacological Prospects
Kinesins are not only transporters but also crucial regulators of mitosis
Drug Discovery Biology
September 17, 2024
Rethinking Preclinical Models in Drug Discovery
The design of new preclinical models should carefully consider both their biological relevance and practical feasibility.
Drug Discovery Biology
September 16, 2024
From Mice to Man: Revolutionizing Drug Discovery with Human-Based Models
As we move toward a future where personalized medicine becomes the norm, the development of human-relevant preclinical models will be critical in bridging the gap between bench and bedside.
Drug Discovery Biology
September 13, 2024
Navigating the Complex Evolution of Preclinical Models
The evolution from traditional to modern lead discovery represents a pivotal moment in drug development.