Drug Discovery Biology

Drug Discovery Biology September 21, 2021

The Latest Drugs to be FDA-approved

The latest drugs to recieve approval offer hope for patients suffering with rare diseases and developmental disorders.

Regulatory Affairs September 9, 2021

The Regulatory Challenges of Cannabis-Derived Drug Products

Very few studies of cannabis-derived drugs have progressed through to clinical trials and passed the strict regulatory process of the FDA.

Drug Discovery Biology September 8, 2021

J&J Scores FDA Approval for Twice-Yearly Schizophrenia drug: Success with Long-acting Injectables

High relapse rates remain a critical problem for patients with schizophrenia, however J&J’s promising schizophrenia drug recieves approval.

Drug Discovery Biology September 1, 2021

The Latest Innovations in Metabolomics

Metabolomics has become an important part of biomarker research; recent studies have shown how it potentially be used as diagnostic tool.

Pharmacovigilance August 17, 2021

The For and Against of Off-Label Drugs

Off-label use has shown success in a number of therapeutic areas, however, the regulation of off-label information continues to cause concern.

Drug Discovery Biology August 16, 2021

RNA Therapeutics: The World’s First mRNA Malaria Vaccine

The approach to addressing the malaria crisis has shifted in recent times, with a number of companies focusing on developing mRNA vaccines.

Featured August 11, 2021

The Latest Innovations in High Throughput Technology: Applications Other Than Drug Discovery

High-throughput technology has historically revolutionised drug discovery. But its latest applications offer potential in many other fields too.

Medicinal Chemistry & Pharmacology August 10, 2021

How Can Microcrystal Electron Diffraction Advance Drug Development?

MicroED can accelerate drug development and determine molecular structure quickly. Despite slow adoption, pharma is increasingly using it in studies.

Drug Discovery Biology July 22, 2021

Implication of the Gut Microbiome in Disease State

Research continues to investigate the link between the gut microbiome and diseases like multiple sclerosis and cancer therapy side effects.

Drug Discovery Biology July 15, 2021

RNA Therapeutics: Innovations in Disease Research and Drug Development

RNA has proven to be a valid therapeutic target for a many diseases. We look at the positive outcomes from research into this molecule.

Drug Discovery Biology July 7, 2021

The Importance of Automation in Pharmacovigilance

Automation has the power to change pharmacovigilance, massively decreasing timelines and increasing the safety of new drugs immensely.

Drug Discovery Biology July 6, 2021

How is Mass Spectrometry Used in Drug Development?

Pharmacokinetics studies are one of the many areas within drug development in which mass spectrometry continues to be an important tool.

Drug Discovery Biology June 22, 2021

Strategies Implemented for New Modalities of Therapeutic Targeting: ASOs and RNAi

siRNAs and antisense oligonucleotides (ASOs) are a few examples of oligonucleotide-platforms making exciting waves in drug discovery.

Drug Discovery Biology June 21, 2021

Using Translational Research to Bridge the Gap Between Preclinical and Clinical Research

Non-traditional animal models and GWAS are examples of innovations in a translational research approach supporting drug development.

Drug Discovery Biology June 16, 2021

Evaluating Advancements in Drug Discovery

Innovations in medicinal chemistry have seen significant developments in drug discovery. Fragment screening is a prime example.

Drug Discovery Biology June 8, 2021

Targeted Protein Degradation: A Potential Tool for Discovering Druggable Targets

Targeted protein degradation is making great strides in targeting ‘undruggable’ targets, overcoming challenges like drug resistance.

Drug Discovery Biology June 1, 2021

Exploring the Latest Therapeutic Tools and In Vitro Technologies

3D culture and organ-on-chip are a few examples of the innovations in preclinical modelling to improve the representation of human physiology.

Drug Discovery Biology May 12, 2021

Implementation of Machine Learning in Drug Development

Significant recent investment in computational biology has seen new innovations in drug discovery – perhaps most notably in machine learning.

Drug Discovery Biology May 5, 2021

Phenotypic Screening in Early Drug Discovery: Opportunities and Challenges

Phenotypic screening is emerging as a popular method in early drug discovery. AI innovations have been shown to optimise current techniques.

Drug Discovery Biology April 27, 2021

Challenges of Modelling Human Disease – Optimising Target Validation

In addition to popular animal models, innovations in computational biology have seen significant advancements in modelling human disease.

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