Immunology & Oncology

Immunology & Oncology December 20, 2024

The Silent Guardian: How GAS1 Shapes the Landscape of Metastatic Melanoma

GAS1’s discovery represents a beacon of hope in the fight against metastatic disease.

Immunology & Oncology December 20, 2024

Resistance Mechanisms Unveiled: The Role of Glutathione S-Transferase in Cancer Therapy Failures

Understanding this dual role of GSTs as both protectors and accomplices to malignancies is central to tackling drug resistance.

Immunology & Oncology December 19, 2024

An Oncological Breakthrough: Envonalkib Outperforms Crizotinib in Treating ALK-Positive Lung Cancer

Genetic and environmental factors affecting NSCLC progression and treatment response necessitate global validation of these envonalkib trial findings.

Immunology & Oncology December 13, 2024

ECM Trafficking and Tumor Invasion: The Hidden Role of Integrin-MAPK Signaling

ECM internalization occurs through macropinocytosis—a process of engulfing extracellular fluid and materials into large vesicles.

Immunology & Oncology December 12, 2024

Cracking the Lipid Code: Plasma Profiling for Early Cancer Detection

Lipidomics has the potential to revolutionize cancer detection and management, transforming patient outcomes and redefining oncology care.

Immunology & Oncology December 3, 2024

Nutrient Partitioning in the Tumor Microenvironment: Mechanisms and Implications

Advancing the understanding of TME metabolism paves the way for targeted cancer therapies tailored to tumor and immune cell metabolic dependencies.

Immunology & Oncology December 2, 2024

Invisible Guardians: The Role of Neutrophil Extracellular Traps in Urinary Tract Defense

The interplay between innate immunity, as exemplified by NETosis, and the structural defenses of the urinary tract highlights the complexity of bladder and kidney immunity.

Immunology & Oncology November 27, 2024

Adhesive Innovation at Subzero: The Next Frontier in Anti-Cancer Drug Delivery

Researchers have engineered a platform that outperforms traditional hydrogels, redefining multifunctionality and efficiency.

Immunology & Oncology November 20, 2024

The Next Frontier in Breast Cancer Prognostics: Artificial Intelligence Revolutionizing Tumor-Infiltrating Lymphocytes Assessment

Tumor-infiltrating lymphocytes are biomarkers of the tumor microenvironment’s dynamics and a patient’s intrinsic anti-tumor immunity.

Immunology & Oncology November 18, 2024

Shape Matters: Studying Cancer Invasion through 3D Tumoroids and Organoids

By bridging the gap between traditional 2D cultures and the complexities of in vivo tumors, ReSCUE provides a powerful tool to unravel the intricacies of cancer biology.

Immunology & Oncology November 11, 2024

The Rhythm of Immunity: How Our Internal Clock Regulates Immune Responses and Metabolism

As our understanding of circadian biology deepens, so too does the potential for circadian-based therapies that restore natural immune and metabolic rhythms.

Immunology & Oncology October 31, 2024

Plasma Cell Leukemia: A Complex Journey from Multiple Myeloma

Given the rarity and aggressiveness of PCL, therapeutic advances will depend on prospective studies examining these cytogenetic markers.

Immunology & Oncology October 29, 2024

Decoding Systemic Sclerosis: The Intricate Web of Immune Mechanisms and Treatment Frontiers

A deeper molecular understanding of systemic sclerosis will likely usher in tailored treatment strategies, potentially combining multiple targeted therapies to address immune abnormalities.

Immunology & Oncology October 25, 2024

miRNA Therapeutics: Bridging the Gap Between Cancer and Neurological Disorders

miRNA therapeutics are in the early stages of development but show significant promise for the treatment of neurological disorders.

Immunology & Oncology October 23, 2024

Understanding Prostate Cancer: The Roles of Chronic Inflammation, Diagnostic Biomarkers, and Lifestyle Modifications

The future of PCa diagnostics lies in the continued refinement of molecular biomarkers and imaging technologies.

Immunology & Oncology October 9, 2024

A New Era in Immunotherapy: Challenges and Potential in Acute Myeloid Leukemia Treatment

Among the promising modern approaches for AML is chimeric antigen receptor (CAR) T cell therapy.

Immunology & Oncology July 30, 2024

Silent Killer: Understanding the Enigma of Pancreatic Ductal Adenocarcinoma

The CAM model represents a significant advancement in cancer research, offering a unique platform for studying tumor growth, perfusion, and metastasis.

Immunology & Oncology March 15, 2024

Forging a Hopeful Outlook on Cancer Drug Development

The core of oncotherapy is still about reducing human suffering and facing the many challenges of this disease together.

Immunology & Oncology February 13, 2024

Patterns, Profiles, and Patient Outcomes: AI in Oncotherapeutics

AI presents a beacon of hope in revolutionizing cancer management across various stages.

Immunology & Oncology January 10, 2024

Novartis’ Strategic Acquisition of Calypso: A Game-Changer in Autoimmune Therapies

IL-15 therapeutics trailblazer Calypso announces a deal to be acquired by Novartis.

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Precision in Three Dimensions: A Novel Approach to Tumor Resection and Reconstruction of the Femoral Trochanter

Blueprint for the Future: Establishing Rigorous Standards for Medical AI Data

Halides in Focus: A Fluorometric Leap for Clinical Diagnostics