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Drug Discovery Biology
February 20, 2025
Thermodynamic Ballet: Enthalpic-Entropic Compensation in Biomolecular Handshakes
Enthalpy-entropy compensation epitomizes the complexity of biomolecular recognition.
Drug Discovery Biology
February 20, 2025
Structural Secrets of SRβ GTPase: Unlocking the Ancient Code of Eukaryotic Membrane Traffic
SRβ, the oldest Ras-family member, connects billion-year-old innovations to modern eukaryotic secretory processes through its structural simplicity and regulatory sophistication.
Medicinal Chemistry & Pharmacology
February 19, 2025
Novel Frontier in Xenobiotic Design: Decoding the Synthetic Accessibility of Drug-Like Molecules
The rise of biocatalysis and flow chemistry demands periodic updates to fragment libraries and complexity metrics.
Medicinal Chemistry & Pharmacology
February 19, 2025
Molecular Alchemy: How MOSES is Redefining Drug Discovery in the Age of AI
MOSES serves as both compass and crucible, guiding researchers through chemical space while rigorously testing their innovations.
