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Medicinal Chemistry & Pharmacology
February 16, 2026
Spatial Collapse: Pharmacologic Degradation of PDEδ to Disrupt Oncogenic KRAS Membrane Localization
PDEδ degradation disrupts KRAS membrane localization to collapse oncogenic signaling through spatial pharmacology rather than direct enzymatic inhibition.
Medicinal Chemistry & Pharmacology
February 4, 2026
Neumedics’ Integrated Innovation Model: Dr. Mark Nelson on Translating Drug Discovery into API Synthesis
Dr. Mark Nelson of Neumedics outlines how integrating medicinal chemistry with scalable API synthesis from the earliest design stages defines the next evolution of pharmaceutical development.
Clinical Operations
February 3, 2026
Zentalis Pharmaceuticals’ Clinical Strategy Architecture: Dr. Stalder on Data Foresight and Oncology Execution
Dr. Joseph Stalder of Zentalis Pharmaceuticals examines how predictive data integration and disciplined program governance are redefining the future of late-stage oncology development.
Medicinal Chemistry & Pharmacology
February 2, 2026
Exelixis Clinical Bioanalysis Leadership, Translational DMPK Craft, and the Kirkovsky Playbook
Senior Director Dr. Leo Kirkovsky brings a rare cross-modality perspective—spanning physical organic chemistry, clinical assay leadership, and ADC bioanalysis—to show how ADME mastery becomes the decision engine that turns complex drug systems into scalable oncology development programs.
Regulatory Affairs
January 30, 2026
Policy Ignition: How Institutional Experiments Become Durable Global Evidence for Pharmaceutical Access
Global pharmaceutical access improves when IP, payment, and real-world evidence systems are engineered as interoperable feedback loops rather than isolated reforms.