Medicinal Chemistry & Pharmacology
July 22, 2024
Permeating the Cranial Center: Novel Nanoparticles for Neurodegeneration
Nanocarriers have demonstrated high effectiveness in delivering drugs and genes to the brain due to their unique properties.
Medicinal Chemistry & Pharmacology
Medicinal Chemistry & Pharmacology
March 25, 2024
Synthetic Chemistry’s Potential in Deciphering Antimicrobial Peptides
The saga of antimicrobial peptides unfolds as a testament to scientific ingenuity and therapeutic resilience.
Medicinal Chemistry & Pharmacology
March 22, 2024
Appreciating the Therapeutic Versatility of the Adenine Scaffold: From Biological Signaling to Disease Treatment
Researchers are utilizing adenine analogs to create potent inhibitors and agonists, targeting vital cellular pathways from cancer to infectious diseases.
Medicinal Chemistry & Pharmacology
March 18, 2024
Bioavailability and Bioequivalence: The Makings of Similar and “Close Enough” Drug Formulations
Scientists are striving to understand bioavailability complexities to ensure the equivalence of drug formulations from different manufacturers, crucial for clinical effectiveness.
Medicinal Chemistry & Pharmacology
March 13, 2024
Primer on Applied Biopharmaceutics and Pharmacokinetics: Part III
In the third part of the Biopharm and PK PharmaFEATURES Primer, we take a deeper dive in mathematical modeling to better estimate drug dosing and generate better predictions of drug efficacy vs time of medications.
Medicinal Chemistry & Pharmacology
March 11, 2024
Bioavailability: Deciphering the Dynamics of Drug Absorption and Distribution
Bioavailability, fundamental in pharmacology, explores intricate drug absorption and distribution in the body.
Medicinal Chemistry & Pharmacology
March 7, 2024
Primer on Applied Biopharmaceutics and Pharmacokinetics: Part II
Plasma drug concentrations monitoring allows medication dose adjustment for individualized and optimized drug therapies.
Medicinal Chemistry & Pharmacology
March 6, 2024
Balancing Act: Optimizing Physicochemical Properties for Successful Drug Discovery
A drug’s physicochemical properties play a crucial role in their effectiveness and safety.
Medicinal Chemistry & Pharmacology
February 29, 2024
QSAR Modeling Improves Understanding of Serotonin Neuropharmacology
QSAR promises to improve serotonin studies.
Medicinal Chemistry & Pharmacology
February 26, 2024
Navigating Drug Toxicity: Insights into Pharmacological Peril
Understanding drug toxicity mechanisms is vital for patient safety and treatment efficacy.
Medicinal Chemistry & Pharmacology
February 21, 2024
Target Locked, Hit Confirmed: A Drug Discovery Mission Possible
The path from target identification to hit discovery showcases the scientific community’s ingenuity and perseverance.
Medicinal Chemistry & Pharmacology
February 16, 2024
Fragment-Based Drug Discovery: A Comprehensive Overview
This FBDD article discusses its fundamental principles, workflow, library selection criteria, expansion strategies, and optimization approaches.
Medicinal Chemistry & Pharmacology
February 8, 2024
The So-Needed Revolution: Advanced Technologies in Cancer Biomedical Discovery
Let’s explore how advanced technologies are actively transforming biomedical discovery, particularly in cancer research.
Medicinal Chemistry & Pharmacology
February 5, 2024
Achieving Drug Formulation Precision through Drug Absorption Models
As costs soar and drug approvals dwindle, research-based companies face a formidable challenge—addressing poorly soluble drug candidates.
Medicinal Chemistry & Pharmacology
January 31, 2024
Targeted Protein Degradation: An Exploration of Modalities and Challenges
Targeted protein degradation proximity agents are emerging modalities in biology and drug discovery.
